Version 5.4
Bos taurus Gene: LEPROT
Summary
InnateDB Gene IDBG-638313.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LEPROT
Gene Name Leptin receptor gene-related protein
Synonyms OB-RGRP
Species Bos taurus
Ensembl Gene ENSBTAG00000005909
Encoded Proteins
IDBP-690376
Leptin receptor gene-related protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213625:
LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]).[supplied by OMIM, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:80243543-80254246
Strand Reverse strand
Band
Transcripts
ENSBTAT00000007762 ENSBTAP00000007762
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0000139 Golgi membrane
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
ENSMUSG00000035212
View Gene Order
ENSG00000213625
View Gene Order
Cross-References
SwissProt Q3SYT0
TrEMBL
UniProt Splice Variant
Entrez Gene 613665
UniGene Bt.20776
RefSeq NM_001034741 XM_005204483
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103409
GenPept AAI03410
RNA Seq Atlas 613665

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca