Version 5.4
Bos taurus Gene: PTPLA
Summary
InnateDB Gene IDBG-638356.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTPLA
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000033089
Encoded Proteins
IDBP-690426
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165996:
The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:32347676-32369621
Strand Reverse strand
Band
Transcripts
ENSBTAT00000046976 ENSBTAP00000044220
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0014902 myotube differentiation
GO:2000045 regulation of G1/S transition of mitotic cell cycle
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000165996
View Gene Order
ENSMUSG00000063275
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa01040
Biosynthesis of unsaturated fatty acids pathway
hsa00062
Fatty acid elongation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MXJ1
UniProt Splice Variant
Entrez Gene 615191
UniGene Bt.23355
RefSeq XM_002692104 XM_866930
HUGO HGNC:9639
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02035577
GenPept
RNA Seq Atlas 615191

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca