Version 5.4
Bos taurus Gene: TNFRSF13B
Summary
InnateDB Gene IDBG-638376.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNFRSF13B
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015298
Encoded Proteins
IDBP-690437
tumor necrosis factor receptor superfamily, member 13B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000240505:
The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:35711779-35721867
Strand Forward strand
Band
Transcripts
ENSBTAT00000020341 ENSBTAP00000020341
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001782 B cell homeostasis
GO:0002244 hematopoietic progenitor cell differentiation
GO:0030889 negative regulation of B cell proliferation
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
ENSMUSG00000010142
View Gene Order
ENSG00000240505
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
mmu04060
Cytokine-cytokine receptor interaction pathway
mmu05340
Primary immunodeficiency pathway
mmu04672
Intestinal immune network for IgA production pathway
hsa04060
Cytokine-cytokine receptor interaction pathway
hsa05340
Primary immunodeficiency pathway
hsa04672
Intestinal immune network for IgA production pathway
INOH
PID NCI
syndecan_2_pathway
Syndecan-2-mediated signaling events
syndecan_4_pathway
Syndecan-4-mediated signaling events
Cross-References
SwissProt
TrEMBL F1MU29
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:18153
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049010 DAAA02049011 DAAA02049012
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca