Version 5.4
Homo sapiens Gene: PLEKHB1
Summary
InnateDB Gene IDBG-63848.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLEKHB1
Gene Name pleckstrin homology domain containing, family B (evectins) member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000021300
Encoded Proteins
IDBP-63850
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-63852
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-232942
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-232944
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-586373
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-590516
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-593952
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-595770
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-594034
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-599363
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-591512
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-595601
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-593017
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-585480
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-599155
pleckstrin homology domain containing, family B (evectins) member 1
IDBP-602893
pleckstrin homology domain containing, family B (evectins) member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:73646178-73662819
Strand Forward strand
Band q13.4
Transcripts
ENST00000354190 ENSP00000346127
ENST00000227214 ENSP00000227214
ENST00000398494 ENSP00000381507
ENST00000398492 ENSP00000381505
ENST00000426191
ENST00000536527 ENSP00000440122
ENST00000543085 ENSP00000441224
ENST00000544532
ENST00000545798 ENSP00000443899
ENST00000539157 ENSP00000445990
ENST00000546251 ENSP00000439714
ENST00000535582 ENSP00000438809
ENST00000538227 ENSP00000445807
ENST00000541760
ENST00000543524 ENSP00000444453
ENST00000541597 ENSP00000442136
ENST00000535129 ENSP00000442616
ENST00000542389 ENSP00000440102
ENST00000540431 ENSP00000441558
ENST00000540157
ENST00000545106
ENST00000544282
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 5 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0007275 multicellular organismal development
GO:0007602 phototransduction
GO:0045595 regulation of cell differentiation
Cellular Component
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030701
View Gene Order
ENSBTAG00000009830
Not yet available
Cross-References
SwissProt Q9UF11
TrEMBL A0A024R5H7 F5GZH3 F5H190 F5H3M1 F5H866
UniProt Splice Variant
Entrez Gene 58473
UniGene Hs.445489
RefSeq NM_001130036 NM_001130033 NM_001130034 NM_001130035 NM_021200
HUGO HGNC:19079
OMIM 607651
CCDS CCDS44675 CCDS44672 CCDS44673 CCDS44674
HPRD 09630
IMGT
EMBL AF081583 AF093249 AF100612 AF101054 AK289620 AK289909 AK290109 AK301299 AK314748 AP000860 AP002993 BC008075 CH471076 U89715
GenPept AAF16675 AAF16684 AAF18572 AAF18932 AAF21786 AAH08075 BAF82309 BAF82598 BAF82798 BAG37288 BAH13452 EAW74900 EAW74903 EAW74904 EAW74906
RNA Seq Atlas 58473

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca