InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: FAR2

Summary

InnateDB Gene

IDBG-638574.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FAR2

Gene Name

Fatty acyl-CoA reductase 2

Synonyms

MLSTD1

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011095

Encoded Proteins

IDBP-690654

Fatty acyl-CoA reductase 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000064763:
This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22. [provided by RefSeq, Nov 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:80665382-80721457

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000014725

ENSBTAP00000014725

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050062	long-chain-fatty-acyl-CoA reductase activity
GO:0050662	coenzyme binding
GO:0051287	NAD binding
GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity

Biological Process

GO:0006629	lipid metabolic process
GO:0006694	steroid biosynthetic process
GO:0009058	biosynthetic process
GO:0035336	long-chain fatty-acyl-CoA metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005777	peroxisome
GO:0005778	peroxisomal membrane
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane