Version 5.4
Bos taurus Gene: ANAPC13
Summary
InnateDB Gene IDBG-638793.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANAPC13
Gene Name Anaphase-promoting complex subunit 13
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014461
Encoded Proteins
IDBP-690891
Anaphase-promoting complex subunit 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129055:
This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:135945605-135951507
Strand Forward strand
Band
Transcripts
ENSBTAT00000019228 ENSBTAP00000019228
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007049 cell cycle
GO:0007067 mitotic nuclear division
GO:0016567 protein ubiquitination
GO:0051301 cell division
GO:0070979 protein K11-linked ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005680 anaphase-promoting complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000129055
View Gene Order
ENSMUSG00000035048
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_230745
Immune System pathway
REACT_199115
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_229531
Adaptive Immune System pathway
KEGG
hsa04110
Cell cycle pathway
hsa04120
Ubiquitin mediated proteolysis pathway
hsa04914
Progesterone-mediated oocyte maturation pathway
hsa04114
Oocyte meiosis pathway
mmu04120
Ubiquitin mediated proteolysis pathway
mmu04110
Cell cycle pathway
mmu04914
Progesterone-mediated oocyte maturation pathway
mmu04114
Oocyte meiosis pathway
INOH
PID NCI
Cross-References
SwissProt Q2NKV2
TrEMBL
UniProt Splice Variant
Entrez Gene 614347
UniGene Bt.20877
RefSeq NM_001113229 NM_001113234
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC111620
GenPept AAI11621
RNA Seq Atlas 614347

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca