Homo sapiens Gene: ANAPC13
Summary
InnateDB Gene IDBG-57556.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANAPC13
Gene Name anaphase promoting complex subunit 13
Synonyms APC13; SWM1
Species Homo sapiens
Ensembl Gene ENSG00000129055
Encoded Proteins
anaphase promoting complex subunit 13
anaphase promoting complex subunit 13
anaphase promoting complex subunit 13
anaphase promoting complex subunit 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:134477706-134486716
Strand Reverse strand
Band q22.2
Transcripts
ENST00000354910 ENSP00000346987
ENST00000510994 ENSP00000421842
ENST00000514612 ENSP00000427327
ENST00000511751 ENSP00000421760
ENST00000508755
ENST00000503439
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
Experimentally validated
Total 28 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007067 mitotic nuclear division
GO:0070979 protein K11-linked ubiquitination
Cellular Component
GO:0005680 anaphase-promoting complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
KEGG
Cell cycle pathway
Ubiquitin mediated proteolysis pathway
Progesterone-mediated oocyte maturation pathway
Oocyte meiosis pathway
INOH
PID NCI
Cross-References
SwissProt Q9BS18
TrEMBL A8K3Z6
UniProt Splice Variant
Entrez Gene 25847
UniGene Hs.106909
RefSeq NM_001242374 NM_001242375 NM_015391
HUGO HGNC:24540
OMIM 614484
CCDS CCDS3085
HPRD 08531
IMGT
EMBL AK290761 AL050051 BC005398 CH471052
GenPept AAH05398 BAF83450 CAB43251 EAW79143 EAW79145 EAW79147 EAW79149
RNA Seq Atlas 25847