Version 5.4
Bos taurus Gene: CNTRL
Summary
InnateDB Gene IDBG-638848.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNTRL
Gene Name Uncharacterized protein
Synonyms CEP110
Species Bos taurus
Ensembl Gene ENSBTAG00000011417
Encoded Proteins
IDBP-691017
centriolin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119397:
This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centrosomal protein 1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:112418136-112498495
Strand Forward strand
Band
Transcripts
ENSBTAT00000061592 ENSBTAP00000053866
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000119397
View Gene Order
ENSMUSG00000057110
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160315
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_15364
Loss of Nlp from mitotic centrosomes pathway
REACT_15451
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_15296
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_115566
Cell Cycle pathway
REACT_15479
Centrosome maturation pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
REACT_245720
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_240530
G2/M Transition pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_189085
Disease pathway
REACT_243078
Loss of Nlp from mitotic centrosomes pathway
REACT_188177
Signaling by FGFR in disease pathway
REACT_188804
Cell Cycle pathway
REACT_246508
Mitotic G2-G2/M phases pathway
REACT_244487
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_196635
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_196455
Signaling by FGFR mutants pathway
REACT_196452
Signaling by FGFR1 mutants pathway
REACT_196460
Signaling by FGFR1 fusion mutants pathway
REACT_253753
Centrosome maturation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.107413 Bt.91526
RefSeq XM_002689962 XM_005199317 XM_005199318 XM_005199319 XM_005199320 XM_005199322 XM_005210615 XM_005210616 XM_005210617 XM_005210618 XM_005210620 XM_598421
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca