Version 5.4
Bos taurus Gene: GIP
Summary
InnateDB Gene IDBG-638853.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GIP
Gene Name Gastric inhibitory polypeptide
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005045
Encoded Proteins
IDBP-690952
Gastric inhibitory polypeptide
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159224:
This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:38202539-38207784
Strand Forward strand
Band
Transcripts
ENSBTAT00000006656 ENSBTAP00000006656
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0007613 memory
GO:0008344 adult locomotory behavior
GO:0019233 sensory perception of pain
GO:0031018 endocrine pancreas development
GO:0035640 exploration behavior
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000159224
View Gene Order
ENSMUSG00000014351
View Gene Order
Pathways
NETPATH
REACTOME
REACT_210701
Peptide hormone metabolism pathway
REACT_205221
Incretin synthesis, secretion, and inactivation pathway
REACT_220607
Glucagon-type ligand receptors pathway
REACT_205369
Signaling by GPCR pathway
REACT_206547
G alpha (s) signalling events pathway
REACT_214353
Signal Transduction pathway
REACT_213782
Metabolism of proteins pathway
REACT_225796
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) pathway
REACT_214436
GPCR downstream signaling pathway
REACT_220217
GPCR ligand binding pathway
REACT_204109
Class B/2 (Secretin family receptors) pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19327
G alpha (s) signalling events pathway
REACT_18377
Glucagon-type ligand receptors pathway
REACT_18372
Class B/2 (Secretin family receptors) pathway
REACT_23824
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_23974
Incretin synthesis, secretion, and inactivation pathway
REACT_17015
Metabolism of proteins pathway
REACT_21340
GPCR ligand binding pathway
REACT_160078
Peptide hormone metabolism pathway
REACT_242871
G alpha (s) signalling events pathway
REACT_231304
Glucagon-type ligand receptors pathway
REACT_223625
GPCR downstream signaling pathway
REACT_230557
Incretin synthesis, secretion, and inactivation pathway
REACT_254215
Signaling by GPCR pathway
REACT_250061
Class B/2 (Secretin family receptors) pathway
REACT_247926
Metabolism of proteins pathway
REACT_206913
Peptide hormone metabolism pathway
REACT_231468
GPCR ligand binding pathway
REACT_188257
Signal Transduction pathway
REACT_253751
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) pathway
KEGG
INOH
INOH website
GPCR signaling pathway
INOH website
GPCR signaling pathway
PID NCI
Cross-References
SwissProt P09680
TrEMBL B3RFM7 F1MQC0
UniProt Splice Variant
Entrez Gene 511073
UniGene Bt.62398
RefSeq NM_001166605
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049055 DQ160296
GenPept ABA03019
RNA Seq Atlas 511073

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca