Bos taurus Gene: AP1S2 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-638864.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | AP1S2 | ||||||||||||
Gene Name | AP-1 complex subunit sigma-2 | ||||||||||||
Synonyms | AP1S1 | ||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000020420 | ||||||||||||
Encoded Proteins |
AP-1 complex subunit sigma-2
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182287:
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome X:134965647-134991291 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Golgi Associated Vesicle Biogenesis pathway
Immune System pathway
Clathrin derived vesicle budding pathway
MHC class II antigen presentation pathway
trans-Golgi Network Vesicle Budding pathway
Adaptive Immune System pathway
Lysosome Vesicle Biogenesis pathway
Membrane Trafficking pathway
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KEGG | |||||||||||||
INOH | |||||||||||||
PID NCI | |||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
MHC class II antigen presentation pathway
Nef mediated downregulation of MHC class I complex cell surface expression pathway
Lysosome Vesicle Biogenesis pathway
Golgi Associated Vesicle Biogenesis pathway
Clathrin derived vesicle budding pathway
trans-Golgi Network Vesicle Budding pathway
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters pathway
Adaptive Immune System pathway
Immune System pathway
HIV Infection pathway
The role of Nef in HIV-1 replication and disease pathogenesis pathway
Host Interactions of HIV factors pathway
Disease pathway
Membrane Trafficking pathway
Membrane Trafficking pathway
Lysosome Vesicle Biogenesis pathway
Immune System pathway
Golgi Associated Vesicle Biogenesis pathway
MHC class II antigen presentation pathway
trans-Golgi Network Vesicle Budding pathway
Clathrin derived vesicle budding pathway
Adaptive Immune System pathway
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KEGG |
Lysosome pathway
Lysosome pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q3ZBS3 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 616331 | ||||||||||||
UniGene | Bt.49367 | ||||||||||||
RefSeq | NM_001040591 XM_005228451 XM_005228452 XM_005228453 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | BC103139 | ||||||||||||
GenPept | AAI03140 | ||||||||||||
RNA Seq Atlas | 616331 | ||||||||||||