InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SLC2A8

Summary

InnateDB Gene

IDBG-638904.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC2A8

Gene Name

solute carrier family 2, facilitated glucose transporter member 8

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000006957

Encoded Proteins

IDBP-691012

solute carrier family 2, facilitated glucose transporter member 8

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136856:
This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:98161639-98170664

Strand

Forward strand

Band

Transcripts

ENSBTAT00000009144

ENSBTAP00000009144

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005355	glucose transmembrane transporter activity
GO:0005536	glucose binding
GO:0022857	transmembrane transporter activity
GO:0022891	substrate-specific transmembrane transporter activity

Biological Process

GO:0001666	response to hypoxia
GO:0006810	transport
GO:0008286	insulin receptor signaling pathway
GO:0015758	glucose transport
GO:0055085	transmembrane transport