Version 5.4
Mus musculus Gene: Slc2a8
Summary
InnateDB Gene IDBG-162096.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc2a8
Gene Name solute carrier family 2, (facilitated glucose transporter), member 8
Synonyms D2Ertd44e; GLUT8; GlutX1
Species Mus musculus
Ensembl Gene ENSMUSG00000026791
Encoded Proteins
IDBP-162098
solute carrier family 2, (facilitated glucose transporter), member 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136856:
This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:32972990-32982083
Strand Reverse strand
Band B
Transcripts
ENSMUST00000028129 ENSMUSP00000028129
ENSMUST00000130769
ENSMUST00000153484
ENSMUST00000123643
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005354 galactose transmembrane transporter activity
GO:0005355 glucose transmembrane transporter activity
GO:0005536 glucose binding
GO:0015284 fructose uniporter activity
GO:0022857 transmembrane transporter activity
GO:0022891 substrate-specific transmembrane transporter activity
Biological Process
GO:0001666 response to hypoxia
GO:0006006 glucose metabolic process
GO:0007141 male meiosis I
GO:0008286 insulin receptor signaling pathway
GO:0015755 fructose transport
GO:0015757 galactose transport
GO:0015758 glucose transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005765 lysosomal membrane
GO:0005887 integral component of plasma membrane
GO:0008021 synaptic vesicle
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030659 cytoplasmic vesicle membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136856
View Gene Order
ENSBTAG00000006957
Not yet available
Pathways
NETPATH
REACTOME
REACT_217615
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_206357
Facilitative Na+-independent glucose transporters pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19343
Facilitative Na+-independent glucose transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9JIF3
TrEMBL
UniProt Splice Variant
Entrez Gene 56017
UniGene
RefSeq NM_019488
OMIM
CCDS CCDS15937
HPRD
IMGT
MGI ID MGI:1860103
MGI Symbol Slc2a8
EMBL AF232061 AJ245936 AJ413951 AK081806 AK170319 AL731852 AY856043 BC090993 CH466542 Y17802
GenPept AAF78366 AAH90993 AAX51785 BAC38338 BAE41714 CAB75719 CAB89815 CAC88690 CAM22323 EDL08590
RNA Seq Atlas 56017

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca