Version 5.4
Bos taurus Gene: BT.24395
Summary
InnateDB Gene IDBG-638960.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.24395
Gene Name Kv channel-interacting protein 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016343
Encoded Proteins
IDBP-691094
Kv channel interacting protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120049:
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:22422214-22440709
Strand Reverse strand
Band
Transcripts
ENSBTAT00000021742 ENSBTAP00000021742
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0015459 potassium channel regulator activity
GO:0042802 identical protein binding
GO:0044325 ion channel binding
GO:0046872 metal ion binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0045163 clustering of voltage-gated potassium channels
GO:0071435 potassium ion export
GO:0071805 potassium ion transmembrane transport
GO:0086009 membrane repolarization
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000120049
View Gene Order
ENSMUSG00000025221
View Gene Order
Cross-References
SwissProt
TrEMBL F1N410
UniProt Splice Variant
Entrez Gene 540895
UniGene Bt.24395
RefSeq NM_001102250 XM_005225595 XM_005225604 XM_005225605
HUGO HGNC:15522
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02058992
GenPept
RNA Seq Atlas 540895

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca