InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ADI1

Summary

InnateDB Gene

IDBG-639012.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADI1

Gene Name

1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

Synonyms

Fe-ARD; MTCBP-1; Ni-ARD

Species

Bos taurus

Ensembl Gene

ENSBTAG00000005403

Encoded Proteins

IDBP-691127

1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182551:
This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. [provided by RefSeq, May 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:112948194-112954511

Strand

Forward strand

Band

Transcripts

ENSBTAT00000007112

ENSBTAP00000007112

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005506	iron ion binding
GO:0005515	protein binding
GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0051213	dioxygenase activity

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0008652	cellular amino acid biosynthetic process
GO:0009086	methionine biosynthetic process
GO:0019509	L-methionine biosynthetic process from methylthioadenosine
GO:0055114	oxidation-reduction process