Version 5.4
Bos taurus Gene: TOR2A
Summary
InnateDB Gene IDBG-639025.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TOR2A
Gene Name Torsin-2A
Synonyms Prosalusin; Torsin-2A
Species Bos taurus
Ensembl Gene ENSBTAG00000013510
Encoded Proteins
IDBP-691139
Torsin-2A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160404:
This gene encodes a member of the AAA family of adenosine triphosphatases with similarity to Clp proteases and heat shock proteins. Alternative splicing at this locus results in the translation of multiple isoforms of the encoded protein, some of which contain salusin peptides in the C-terminal region. These peptides may play roles in hypotension, myocardial growth and the induction of mitogenesis, and may also be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:98425082-98429110
Strand Reverse strand
Band
Transcripts
ENSBTAT00000017963 ENSBTAP00000017963
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0051085 chaperone mediated protein folding requiring cofactor
GO:0051260 protein homooligomerization
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000160404
View Gene Order
ENSMUSG00000009563
View Gene Order
Cross-References
SwissProt A4FUH1
TrEMBL
UniProt Splice Variant
Entrez Gene 534311
UniGene Bt.22232
RefSeq NM_001083476
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114885
GenPept AAI14886
RNA Seq Atlas 534311

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca