Version 5.4
Mus musculus Gene: Tor2a
Summary
InnateDB Gene IDBG-161439.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tor2a
Gene Name torsin family 2, member A
Synonyms Prosalusin
Species Mus musculus
Ensembl Gene ENSMUSG00000009563
Encoded Proteins
IDBP-161441
torsin family 2, member A
IDBP-542219
torsin family 2, member A
IDBP-718999
IDBP-718944
IDBP-719397
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160404:
This gene encodes a member of the AAA family of adenosine triphosphatases with similarity to Clp proteases and heat shock proteins. Alternative splicing at this locus results in the translation of multiple isoforms of the encoded protein, some of which contain salusin peptides in the C-terminal region. These peptides may play roles in hypotension, myocardial growth and the induction of mitogenesis, and may also be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:32757234-32762244
Strand Forward strand
Band B
Transcripts
ENSMUST00000009707 ENSMUSP00000009707
ENSMUST00000156617 ENSMUSP00000122251
ENSMUST00000123624
ENSMUST00000140999 ENSMUSP00000135278
ENSMUST00000149720
ENSMUST00000149987
ENSMUST00000177382 ENSMUSP00000134968
ENSMUST00000175763 ENSMUSP00000135701
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0051085 chaperone mediated protein folding requiring cofactor
GO:0051260 protein homooligomerization
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000160404
View Gene Order
ENSBTAG00000013510
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.200695
RefSeq NM_152800 XM_006498123
OMIM
CCDS CCDS15929
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca