Bos taurus Gene: UBA5
Summary
InnateDB Gene IDBG-639036.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBA5
Gene Name Ubiquitin-like modifier-activating enzyme 5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004495
Encoded Proteins
Ubiquitin-like modifier-activating enzyme 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000081307:
This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A pseudogene located on chromosome 1 has also been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:137960492-137993315
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005894 ENSBTAP00000005894
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0046872 metal ion binding
GO:0048037 cofactor binding
GO:0071566 UFM1 activating enzyme activity
Biological Process
GO:0034976 response to endoplasmic reticulum stress
GO:0055114 oxidation-reduction process
GO:0071569 protein ufmylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Class I MHC mediated antigen processing & presentation pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Immune System pathway
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
Class I MHC mediated antigen processing & presentation pathway
Immune System pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt A7MAZ3
TrEMBL
UniProt Splice Variant
Entrez Gene 509292
UniGene Bt.17929 Bt.85757
RefSeq NM_001101067
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151254
GenPept AAI51255
RNA Seq Atlas 509292