Version 5.4
Bos taurus Gene: ACPP
Summary
InnateDB Gene IDBG-639066.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACPP
Gene Name Prostatic acid phosphatase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011634
Encoded Proteins
IDBP-691188
Prostatic acid phosphatase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000014257:
This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:138348896-138384864
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015451 ENSBTAP00000015451
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003993 acid phosphatase activity
GO:0005515 protein binding
GO:0008253 5'-nucleotidase activity
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0042131 thiamine phosphate phosphatase activity
GO:0042802 identical protein binding
GO:0052642 lysophosphatidic acid phosphatase activity
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0006772 thiamine metabolic process
GO:0009117 nucleotide metabolic process
GO:0016311 dephosphorylation
GO:0046085 adenosine metabolic process
GO:0051930 regulation of sensory perception of pain
GO:0060168 positive regulation of adenosine receptor signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0012506 vesicle membrane
GO:0016021 integral component of membrane
GO:0030175 filopodium
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000014257
View Gene Order
ENSMUSG00000032561
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00740
Riboflavin metabolism pathway
mmu00740
Riboflavin metabolism pathway
INOH
PID NCI
Cross-References
SwissProt A6H730
TrEMBL
UniProt Splice Variant
Entrez Gene 504700
UniGene Bt.61011
RefSeq NM_001098866
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC146093
GenPept AAI46094
RNA Seq Atlas 504700

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca