Bos taurus Gene: NPEPPS
Summary
InnateDB Gene IDBG-639115.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NPEPPS
Gene Name puromycin-sensitive aminopeptidase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011435
Encoded Proteins
aminopeptidase puromycin sensitive
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141279:
This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:39460692-39564822
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015199 ENSBTAP00000015199
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
Class I MHC mediated antigen processing & presentation pathway
Immune System pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BP91
UniProt Splice Variant
Entrez Gene 534122
UniGene Bt.106264 Bt.7723
RefSeq NM_001193159 XM_005220584 XM_005220585
HUGO HGNC:7900
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049085
GenPept
RNA Seq Atlas 534122