Version 5.4
Bos taurus Gene: PDE9A
Summary
InnateDB Gene IDBG-639501.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDE9A
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021899
Encoded Proteins
IDBP-691733
phosphodiesterase 9A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160191:
The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:144493957-144603437
Strand Forward strand
Band
Transcripts
ENSBTAT00000029195 ENSBTAP00000029195
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515 protein binding
GO:0008081 phosphoric diester hydrolase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity
Biological Process
GO:0007165 signal transduction
GO:0008152 metabolic process
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000160191
View Gene Order
ENSMUSG00000041119
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_23767
cGMP effects pathway
REACT_23862
Nitric oxide stimulates guanylate cyclase pathway
REACT_23876
Platelet homeostasis pathway
REACT_604
Hemostasis pathway
REACT_208483
Platelet homeostasis pathway
REACT_224553
Hemostasis pathway
REACT_229620
cGMP effects pathway
REACT_245499
Nitric oxide stimulates guanylate cyclase pathway
KEGG
hsa00230
Purine metabolism pathway
mmu00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
PID NCI
ar_tf_pathway
Regulation of Androgen receptor activity
Cross-References
SwissProt
TrEMBL F1MH30
UniProt Splice Variant
Entrez Gene 511665
UniGene Bt.53856
RefSeq XM_002685134 XM_005192249 XM_005202035 XM_589046
HUGO HGNC:8795
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02003300 DAAA02003301 DAAA02003302 DAAA02003303 DAAA02003304 DAAA02003305 DAAA02003306 DAAA02003307 DAAA02003308
GenPept
RNA Seq Atlas 511665

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca