InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.45031

Summary

InnateDB Gene

IDBG-639846.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.45031

Gene Name

prostacyclin receptor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000014585

Encoded Proteins

IDBP-692038

prostacyclin receptor

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160013:
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:54185871-54188079

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000019413

ENSBTAP00000019413

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity

Biological Process

GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0032496	response to lipopolysaccharide
GO:0043950	positive regulation of cAMP-mediated signaling
GO:0048662	negative regulation of smooth muscle cell proliferation