Version 5.4
Bos taurus Gene: GTF2I
Summary
InnateDB Gene IDBG-639888.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTF2I
Gene Name ral transcription factor II-I
Synonyms GTFII-I; TFII-I
Species Bos taurus
Ensembl Gene ENSBTAG00000009780
Encoded Proteins
IDBP-692102
ral transcription factor II-I
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:33291440-33372706
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012904 ENSBTAP00000012904
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 61 interaction(s) predicted by orthology.
Predicted by orthology
Total 61 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0051019 mitogen-activated protein kinase binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0014886 transition between slow and fast fiber
GO:0016525 negative regulation of angiogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0042995 cell projection
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
null
View Gene Order
ENSMUSG00000060261
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
NetPath_12
BCR pathway
REACTOME
KEGG
hsa03022
Basal transcription factors pathway
mmu03022
Basal transcription factors pathway
INOH
PID NCI
Cross-References
SwissProt A7MB80
TrEMBL
UniProt Splice Variant
Entrez Gene 534669
UniGene Bt.10542
RefSeq NM_001102177 XM_005225177
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151387
GenPept AAI51388
RNA Seq Atlas 534669

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca