Version 5.4
Bos taurus Gene: BT.63571
Summary
InnateDB Gene IDBG-640011.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.63571
Gene Name 2-hydroxyacylsphingosine 1-beta-galactosyltransferase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004574
Encoded Proteins
IDBP-692212
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174607:
The protein encoded by this gene belongs to the UDP-glycosyltransferase family. It catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central and peripheral nervous systems. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:12092955-12201473
Strand Reverse strand
Band
Transcripts
ENSBTAT00000006007 ENSBTAP00000006007
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups
GO:0016758 transferase activity, transferring hexosyl groups
GO:0030246 carbohydrate binding
Biological Process
GO:0002175 protein localization to paranode region of axon
GO:0005975 carbohydrate metabolic process
GO:0007010 cytoskeleton organization
GO:0008088 axon cargo transport
GO:0008152 metabolic process
GO:0030259 lipid glycosylation
GO:0030913 paranodal junction assembly
GO:0048812 neuron projection morphogenesis
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000174607
View Gene Order
ENSMUSG00000032854
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00600
Sphingolipid metabolism pathway
mmu00600
Sphingolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F6RP42
UniProt Splice Variant
Entrez Gene 281566
UniGene Bt.63571 Bt.72112
RefSeq NM_001083635
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02016452
GenPept
RNA Seq Atlas 281566

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca