Version 5.4
Bos taurus Gene: SEPW1
Summary
InnateDB Gene IDBG-640058.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEPW1
Gene Name selenoprotein W
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008203
Encoded Proteins
IDBP-692334
selenoprotein W, 1
IDBP-692336
selenoprotein W, 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178980:
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein shows highest expression in skeletal muscle and heart, and may be involved in oxidation-reduction reactions. A retroprocessed pseudogene, SEPW1P, has been identified and mapped to chromosome 1p35-34. [provided by RefSeq, Jul 2008]
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3\' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein shows highest expression in skeletal muscle and heart, and may be involved in oxidation-reduction reactions. A retroprocessed pseudogene, SEPW1P, has been identified and mapped to chromosome 1p35-34. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:55112228-55116590
Strand Forward strand
Band
Transcripts
ENSBTAT00000066166 ENSBTAP00000054665
ENSBTAT00000010788 ENSBTAP00000010788
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008430 selenium binding
Biological Process
GO:0045454 cell redox homeostasis
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000178980
View Gene Order
ENSMUSG00000041571
View Gene Order
Cross-References
SwissProt
TrEMBL G3MYM9 G5E5A2
UniProt Splice Variant
Entrez Gene 523694
UniGene
RefSeq NM_001163225
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047428 DAAA02047429
GenPept
RNA Seq Atlas 523694

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca