Mus musculus Gene: Sepw1
Summary
InnateDB Gene IDBG-145591.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sepw1
Gene Name selenoprotein W, muscle 1
Synonyms selW
Species Mus musculus
Ensembl Gene ENSMUSG00000041571
Encoded Proteins
selenoprotein W, muscle 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3\' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein has been shown to function as a glutathione-dependent antioxidant in vivo. It is highly expressed in proliferating myoblasts and suggested to be involved in muscle growth and differentiation by protecting the developing myoblasts from oxidative stress. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:15917210-15922371
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000044355 ENSMUSP00000038943
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008430 selenium binding
GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt P63300
TrEMBL
UniProt Splice Variant
Entrez Gene 20364
UniGene
RefSeq NM_009156
OMIM
CCDS CCDS39778
HPRD
IMGT
MGI ID MGI:1100878
MGI Symbol Sepw1
EMBL AF015284 AF241527 AK002870 AK028124 BC052719 U67890
GenPept AAB69860 AAC53317 AAF64481 AAH52719 BAC55247 BAC55256
RNA Seq Atlas 20364