Version 5.4
Bos taurus Gene: NASP
Summary
InnateDB Gene IDBG-640062.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NASP
Gene Name Nuclear autoantigenic sperm protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015346
Encoded Proteins
IDBP-692276
Nuclear autoantigenic sperm protein
IDBP-692279
Nuclear autoantigenic sperm protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132780:
This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:101062575-101090570
Strand Reverse strand
Band
Transcripts
ENSBTAT00000020401 ENSBTAP00000020401
ENSBTAT00000057267 ENSBTAP00000048905
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042393 histone binding
GO:0051879 Hsp90 protein binding
Biological Process
GO:0001824 blastocyst development
GO:0006260 DNA replication
GO:0006335 DNA replication-dependent nucleosome assembly
GO:0006336 DNA replication-independent nucleosome assembly
GO:0006810 transport
GO:0007049 cell cycle
GO:0008283 cell proliferation
GO:0015031 protein transport
GO:0043486 histone exchange
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000132780
View Gene Order
ENSMUSG00000028693
View Gene Order
Cross-References
SwissProt Q2T9P4
TrEMBL A5D969
UniProt Splice Variant
Entrez Gene 512427
UniGene Bt.18798
RefSeq NM_001038088 XM_005204708 XM_005204709
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC111329 BT030488 DAAA02009005
GenPept AAI11330 ABQ12928
RNA Seq Atlas 512427

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca