Version 5.4
Mus musculus Gene: Nasp
Summary
InnateDB Gene IDBG-178322.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nasp
Gene Name nuclear autoantigenic sperm protein (histone-binding)
Synonyms 5033430J04Rik; AI131596; AI317140; D4Ertd767e; Epcs32; Nasp-T
Species Mus musculus
Ensembl Gene ENSMUSG00000028693
Encoded Proteins
IDBP-178324
nuclear autoantigenic sperm protein (histone-binding)
IDBP-178326
nuclear autoantigenic sperm protein (histone-binding)
IDBP-178328
nuclear autoantigenic sperm protein (histone-binding)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132780:
This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:116601052-116627941
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000030457 ENSMUSP00000030457
ENSMUST00000030456 ENSMUSP00000030456
ENSMUST00000081182 ENSMUSP00000079946
ENSMUST00000155398
ENSMUST00000130363
ENSMUST00000154811
ENSMUST00000134038
ENSMUST00000148436
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042393 histone binding
GO:0051879 Hsp90 protein binding
Biological Process
GO:0001824 blastocyst development
GO:0006260 DNA replication
GO:0006335 DNA replication-dependent nucleosome assembly
GO:0006336 DNA replication-independent nucleosome assembly
GO:0007049 cell cycle
GO:0008283 cell proliferation
GO:0015031 protein transport
GO:0043486 histone exchange
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000132780
View Gene Order
ENSBTAG00000015346
Not yet available
Cross-References
SwissProt Q99MD9
TrEMBL B1AU75 B1AU76 Q3TTH5
UniProt Splice Variant
Entrez Gene 50927
UniGene Mm.257181 Mm.401098 Mm.411401
RefSeq NM_001081475 NM_001284229 NM_016777 XM_006503223 XM_006503224
OMIM
CCDS CCDS18513 CCDS38852 CCDS71451
HPRD
IMGT
MGI ID MGI:1355328
MGI Symbol Nasp
EMBL AF034610 AF095722 AF349432 AK083333 AK132690 AK161367 AL669953 BC004693 BX004835 CH466552
GenPept AAB87567 AAC64195 AAH04693 AAK31170 AAK31171 BAC38871 BAE21303 BAE36350 EDL30598
RNA Seq Atlas 50927

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca