Version 5.4
Bos taurus Gene: BT.27517
Summary
InnateDB Gene IDBG-640108.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.27517
Gene Name pancreatic triacylglycerol lipase precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000032237
Encoded Proteins
IDBP-692368
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175535:
This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:37289807-37310481
Strand Forward strand
Band
Transcripts
ENSBTAT00000001012 ENSBTAP00000001012
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004806 triglyceride lipase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0052689 carboxylic ester hydrolase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0030299 intestinal cholesterol absorption
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000175535
View Gene Order
ENSMUSG00000046008
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_24968
Retinoid metabolism and transport pathway
REACT_9518
Digestion of dietary lipid pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111102
Signal Transduction pathway
REACT_160102
Diseases associated with visual transduction pathway
REACT_160125
Visual phototransduction pathway
REACT_111217
Metabolism pathway
REACT_602
Lipid digestion, mobilization, and transport pathway
REACT_116125
Disease pathway
REACT_189085
Disease pathway
REACT_198569
Retinoid metabolism and transport pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_238381
Lipid digestion, mobilization, and transport pathway
REACT_204917
Digestion of dietary lipid pathway
REACT_188260
Visual phototransduction pathway
REACT_188257
Signal Transduction pathway
REACT_188255
Diseases associated with visual transduction pathway
KEGG
hsa00561
Glycerolipid metabolism pathway
hsa04975
Fat digestion and absorption pathway
hsa04972
Pancreatic secretion pathway
mmu00561
Glycerolipid metabolism pathway
mmu04972
Pancreatic secretion pathway
mmu04975
Fat digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BJQ9
UniProt Splice Variant
Entrez Gene 515764
UniGene Bt.27517
RefSeq NM_001205820
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02059332
GenPept
RNA Seq Atlas 515764

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca