Mus musculus Gene: Pnlip
Summary
InnateDB Gene IDBG-180517.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pnlip
Gene Name pancreatic lipase
Synonyms 1810007A24Rik; PL; PTL
Species Mus musculus
Ensembl Gene ENSMUSG00000046008
Encoded Proteins
pancreatic lipase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175535:
This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:58670365-58681786
Strand Forward strand
Band D2
Transcripts
ENSMUST00000057270 ENSMUSP00000056377
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004806 triglyceride lipase activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0016042 lipid catabolic process
GO:0030299 intestinal cholesterol absorption
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Disease pathway
Retinoid metabolism and transport pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Lipid digestion, mobilization, and transport pathway
Digestion of dietary lipid pathway
Visual phototransduction pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
KEGG
Glycerolipid metabolism pathway
Pancreatic secretion pathway
Fat digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Retinoid metabolism and transport pathway
Digestion of dietary lipid pathway
Metabolism of lipids and lipoproteins pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Visual phototransduction pathway
Metabolism pathway
Lipid digestion, mobilization, and transport pathway
Disease pathway
KEGG
Glycerolipid metabolism pathway
Fat digestion and absorption pathway
Pancreatic secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.20407
RefSeq NM_026925
OMIM
CCDS CCDS29930
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas