InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: YWHAG

Summary

InnateDB Gene

IDBG-640151.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

YWHAG

Gene Name

14-3-3 protein gamma

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004077

Encoded Proteins

IDBP-692374

14-3-3 protein gamma

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170027:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100%% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 25:34884283-34906639

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000005327

ENSBTAP00000005327

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 283 interaction(s) predicted by orthology.

Predicted by orthology
Total	283 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005080	protein kinase C binding
GO:0005159	insulin-like growth factor receptor binding
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0044822	poly(A) RNA binding