Version 5.4
Bos taurus Gene: PSMC3IP
Summary
InnateDB Gene IDBG-640275.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PSMC3IP
Gene Name PSMC3 interacting protein
Synonyms PSMC3IP
Species Bos taurus
Ensembl Gene ENSBTAG00000020907
Encoded Proteins
IDBP-692542
PSMC3 interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131470:
This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:43290562-43295238
Strand Reverse strand
Band
Transcripts
ENSBTAT00000027851 ENSBTAP00000027851
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005506 iron ion binding
GO:0009055 electron carrier activity
GO:0020037 heme binding
GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity
Biological Process
GO:0022900 electron transport chain
GO:0045892 negative regulation of transcription, DNA-templated
GO:2001141 regulation of RNA biosynthetic process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000131470
View Gene Order
ENSMUSG00000019303
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
REACT_27271
Meiotic recombination pathway
REACT_115566
Cell Cycle pathway
REACT_111183
Meiosis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BEL5
UniProt Splice Variant
Entrez Gene 789362
UniGene Bt.30711 Bt.76366
RefSeq NM_001244194 XM_001256138 XM_005220802
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049190
GenPept
RNA Seq Atlas 508530 789362

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca