Version 5.4
Bos taurus Gene: CUX1
Summary
InnateDB Gene IDBG-640277.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CUX1
Gene Name Uncharacterized protein
Synonyms CUTL1
Species Bos taurus
Ensembl Gene ENSBTAG00000010659
Encoded Proteins
IDBP-692573
cut-like homeobox 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000257923:
The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:35243348-35515094
Strand Reverse strand
Band
Transcripts
ENSBTAT00000014098 ENSBTAP00000014098
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001205 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001822 kidney development
GO:0006355 regulation of transcription, DNA-templated
GO:0030324 lung development
GO:0042491 auditory receptor cell differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
ENSMUSG00000029705
View Gene Order
ENSG00000257923
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121141
Signaling by FGFR1 fusion mutants pathway
REACT_121398
Signaling by FGFR mutants pathway
REACT_120736
Signaling by FGFR in disease pathway
REACT_120999
Signaling by FGFR1 mutants pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.8487
RefSeq XM_005193012 XM_005225256 XM_601985
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca