Version 5.4
Bos taurus Gene: TUBG1
Summary
InnateDB Gene IDBG-640316.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUBG1
Gene Name Tubulin gamma-1 chain
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000048152
Encoded Proteins
IDBP-692568
Tubulin gamma-1 chain
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131462:
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:43316471-43321165
Strand Forward strand
Band
Transcripts
ENSBTAT00000064686 ENSBTAP00000055684
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 58 interaction(s) predicted by orthology.
Predicted by orthology
Total 58 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007017 microtubule-based process
GO:0007020 microtubule nucleation
GO:0031122 cytoplasmic microtubule organization
GO:0051258 protein polymerization
Cellular Component
GO:0000930 gamma-tubulin complex
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005827 polar microtubule
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000131462
View Gene Order
ENSMUSG00000035198
View Gene Order
Pathways
NETPATH
REACTOME
REACT_223914
G2/M Transition pathway
REACT_215505
Cell Cycle, Mitotic pathway
REACT_205006
Loss of Nlp from mitotic centrosomes pathway
REACT_217933
Mitotic G2-G2/M phases pathway
REACT_214934
Cell Cycle pathway
REACT_214350
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_215331
Recruitment of NuMA to mitotic centrosomes pathway
REACT_224118
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_215812
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_210400
Centrosome maturation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160315
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_15364
Loss of Nlp from mitotic centrosomes pathway
REACT_15451
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_15510
Recruitment of NuMA to mitotic centrosomes pathway
REACT_15296
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_115566
Cell Cycle pathway
REACT_15479
Centrosome maturation pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
REACT_245720
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_240530
G2/M Transition pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_243078
Loss of Nlp from mitotic centrosomes pathway
REACT_188804
Cell Cycle pathway
REACT_246290
Recruitment of NuMA to mitotic centrosomes pathway
REACT_246508
Mitotic G2-G2/M phases pathway
REACT_244487
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_196635
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_253753
Centrosome maturation pathway
KEGG
INOH
PID NCI
plk1_pathway
PLK1 signaling events
Cross-References
SwissProt Q0VCD2
TrEMBL
UniProt Splice Variant
Entrez Gene 786128
UniGene Bt.62427
RefSeq NM_001076255 XM_001790429
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120225
GenPept AAI20226
RNA Seq Atlas 541101 786128
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca