InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Tubg1

Summary

InnateDB Gene

IDBG-211869.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tubg1

Gene Name

tubulin, gamma 1

Synonyms

1500010O08Rik; AI451582; AI503389; Tubg

Species

Mus musculus

Ensembl Gene

ENSMUSG00000035198

Encoded Proteins

IDBP-211871

tubulin, gamma 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131462:
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:101119938-101126419

Strand

Forward strand

Band

Transcripts

ENSMUST00000043680	ENSMUSP00000048036
ENSMUST00000137844

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	52 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005200	structural constituent of cytoskeleton
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0000212	meiotic spindle organization
GO:0006184	GTP catabolic process
GO:0007020	microtubule nucleation
GO:0007052	mitotic spindle organization
GO:0007088	regulation of mitosis
GO:0031122	cytoplasmic microtubule organization
GO:0051258	protein polymerization

Cellular Component

GO:0000242	pericentriolar material
GO:0000794	condensed nuclear chromosome
GO:0000922	spindle pole
GO:0000930	gamma-tubulin complex
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005814	centriole
GO:0005815	microtubule organizing center
GO:0005827	polar microtubule
GO:0005876	spindle microtubule
GO:0005881	cytoplasmic microtubule
GO:0005929	cilium
GO:0031252	cell leading edge
GO:0031513	nonmotile primary cilium
GO:0036064	ciliary basal body
GO:0043234	protein complex
GO:0045177	apical part of cell