Version 5.4
Bos taurus Gene: CBR1
Summary
InnateDB Gene IDBG-640461.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CBR1
Gene Name carbonyl reductase
Synonyms 9-KPR
Species Bos taurus
Ensembl Gene ENSBTAG00000023384
Encoded Proteins
IDBP-692723
carbonyl reductase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159228:
Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. [provided by RefSeq, Jul 2008]
The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:150054221-150064636
Strand Forward strand
Band
Transcripts
ENSBTAT00000031838 ENSBTAP00000031784
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000159228
View Gene Order
ENSMUSG00000051483
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150149
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) pathway
REACT_147851
Arachidonic acid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_188623
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) pathway
REACT_188625
Arachidonic acid metabolism pathway
KEGG
hsa00590
Arachidonic acid metabolism pathway
hsa00980
Metabolism of xenobiotics by cytochrome P450 pathway
mmu00590
Arachidonic acid metabolism pathway
mmu00980
Metabolism of xenobiotics by cytochrome P450 pathway
INOH
INOH website
Prostaglandin Leukotriene metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL G1K231
UniProt Splice Variant
Entrez Gene 515946
UniGene
RefSeq NM_001034513 XM_005196019 XM_005202070
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02003560 DAAA02003561 DAAA02003562 DAAA02003563
GenPept
RNA Seq Atlas 515946

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca