Bos taurus Gene: CDC20
Summary
InnateDB Gene IDBG-640480.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDC20
Gene Name cell division cycle protein 20 homolog
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009819
Encoded Proteins
cell division cycle protein 20 homolog
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117399:
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008]
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:103238486-103242373
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012945 ENSBTAP00000012945
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 97 interaction(s) predicted by orthology.
Predicted by orthology
Total 97 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0019899 enzyme binding
Biological Process
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031915 positive regulation of synaptic plasticity
GO:0040020 regulation of meiosis
GO:0051488 activation of anaphase-promoting complex activity
GO:0090129 positive regulation of synapse maturation
Cellular Component
GO:0005634 nucleus
GO:0005680 anaphase-promoting complex
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Inactivation of APC/C via direct inhibition of the APC/C complex pathway
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components pathway
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway
APC/C:Cdc20 mediated degradation of Cyclin B pathway
APC/C:Cdc20 mediated degradation of Securin pathway
APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase pathway
SCF-beta-TrCP mediated degradation of Emi1 pathway
Phosphorylation of Emi1 pathway
Regulation of APC/C activators between G1/S and early anaphase pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
APC/C-mediated degradation of cell cycle proteins pathway
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Regulation of mitotic cell cycle pathway
Cell Cycle pathway
Adaptive Immune System pathway
Mitotic Spindle Checkpoint pathway
Immune System pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Class I MHC mediated antigen processing & presentation pathway
Cell Cycle Checkpoints pathway
Mitotic Metaphase and Anaphase pathway
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase pathway
Cell Cycle, Mitotic pathway
Class I MHC mediated antigen processing & presentation pathway
APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Separation of Sister Chromatids pathway
Resolution of Sister Chromatid Cohesion pathway
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Phosphorylation of Emi1 pathway
Cell Cycle pathway
APC/C-mediated degradation of cell cycle proteins pathway
Immune System pathway
M Phase pathway
Cell Cycle Checkpoints pathway
SCF-beta-TrCP mediated degradation of Emi1 pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Regulation of APC/C activators between G1/S and early anaphase pathway
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway
Regulation of mitotic cell cycle pathway
APC/C:Cdc20 mediated degradation of Securin pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Inactivation of APC/C via direct inhibition of the APC/C complex pathway
Adaptive Immune System pathway
Mitotic Spindle Checkpoint pathway
Mitotic Anaphase pathway
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components pathway
APC/C:Cdc20 mediated degradation of Cyclin B pathway
KEGG
Cell cycle pathway
Ubiquitin mediated proteolysis pathway
Oocyte meiosis pathway
Ubiquitin mediated proteolysis pathway
Cell cycle pathway
Oocyte meiosis pathway
INOH
PID NCI
PLK1 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.639
RefSeq NM_001082436 XM_005204731
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas