Bos taurus Gene: PPA2
Summary
InnateDB Gene IDBG-640684.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPA2
Gene Name inorganic pyrophosphatase 2, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002428
Encoded Proteins
inorganic pyrophosphatase 2, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138777:
The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:20984354-21082553
Strand Forward strand
Band
Transcripts
ENSBTAT00000003165 ENSBTAP00000003165
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004427 inorganic diphosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
Biological Process
GO:0006796 phosphate-containing compound metabolic process
GO:0016311 dephosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Mitochondrial tRNA aminoacylation pathway
tRNA Aminoacylation pathway
Gene Expression pathway
tRNA Aminoacylation pathway
Mitochondrial tRNA aminoacylation pathway
Gene Expression pathway
KEGG
Oxidative phosphorylation pathway
Oxidative phosphorylation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q2KIV7
UniProt Splice Variant
Entrez Gene 615820
UniGene Bt.58443
RefSeq NM_001076396
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112492 DAAA02016679 DAAA02016680 DAAA02016681 DAAA02016682
GenPept AAI12493
RNA Seq Atlas 615820