Bos taurus Gene: PNKP | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-640829.3 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | PNKP | ||||||||||
Gene Name | bifunctional polynucleotide phosphatase/kinase | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Gene | ENSBTAG00000001834 | ||||||||||
Encoded Proteins |
bifunctional polynucleotide phosphatase/kinase
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000039650:
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010] This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5\' phosphorylation and 3\' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 18:56666460-56671418 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | |||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME | |||||||||||
KEGG | |||||||||||
INOH | |||||||||||
PID NCI |
DNA-PK pathway in nonhomologous end joining
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Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | A4FV28 F1N3Q9 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 616621 | ||||||||||
UniGene | |||||||||||
RefSeq | |||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | BC123660 DAAA02047486 | ||||||||||
GenPept | AAI23661 | ||||||||||
RNA Seq Atlas | 616621 | ||||||||||