InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: UNC5C

Summary

InnateDB Gene

IDBG-640984.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UNC5C

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002084

Encoded Proteins

IDBP-693317

unc-5 homolog C (C. elegans)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182168:
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:30595881-30785866

Strand

Forward strand

Band

Transcripts

ENSBTAT00000039753

ENSBTAP00000039541

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005042	netrin receptor activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0007420	brain development
GO:0030334	regulation of cell migration
GO:0033564	anterior/posterior axon guidance
GO:0038007	netrin-activated signaling pathway
GO:0043065	positive regulation of apoptotic process