Version 5.4
Bos taurus Gene: SS18L1
Summary
InnateDB Gene IDBG-641019.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SS18L1
Gene Name Calcium-responsive transactivator
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014438
Encoded Proteins
IDBP-693337
Calcium-responsive transactivator
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184402:
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to SS18.[supplied by OMIM, Jul 2002]
This gene encodes a calcium-responsive transactivator which is an essential subunit of a neuron-specific chromatin-remodeling complex. The structure of this gene is similar to that of the SS18 gene. Mutations in this gene are involved in amyotrophic lateral sclerosis (ALS). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:55538716-55566383
Strand Reverse strand
Band
Transcripts
ENSBTAT00000019202 ENSBTAP00000019202
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0016358 dendrite development
GO:0016568 chromatin modification
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0000780 condensed nuclear chromosome, centromeric region
GO:0005634 nucleus
GO:0005694 chromosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000184402
View Gene Order
ENSMUSG00000039086
View Gene Order
Cross-References
SwissProt Q08E31
TrEMBL
UniProt Splice Variant
Entrez Gene 768207
UniGene Bt.72114
RefSeq NM_001078095
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123448
GenPept AAI23449
RNA Seq Atlas 768207

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca