Version 5.4
| Bos taurus Gene: RNF216 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-641071.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | RNF216 | ||||||||
| Gene Name | E3 ubiquitin-protein ligase RNF216 | ||||||||
| Synonyms | TRIAD3 | ||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000017175 | ||||||||
| Encoded Proteins |
ring finger protein 216
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000011275:
This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 25:39160895-39279504 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1BHM7 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 534455 | ||||||||
| UniGene | Bt.43745 | ||||||||
| RefSeq | NM_001193258 | ||||||||
| HUGO | HGNC:21698 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02058349 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 534455 | ||||||||