Version 5.4
Bos taurus Gene: SMARCAD1
Summary
InnateDB Gene IDBG-641078.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMARCAD1
Gene Name SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017061
Encoded Proteins
IDBP-693411
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163104:
This gene encodes a member of the SNF subfamily of helicase proteins. The encoded protein plays a critical role in the restoration of heterochromatin organization and propagation of epigenetic patterns following DNA replication by mediating histone H3/H4 deacetylation. Mutations in this gene are associated with adermatoglyphia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:31733506-31821888
Strand Reverse strand
Band
Transcripts
ENSBTAT00000047936 ENSBTAP00000045084
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 107 interaction(s) predicted by orthology.
Predicted by orthology
Total 107 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000018 regulation of DNA recombination
GO:0000729 DNA double-strand break processing
GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus
GO:0016568 chromatin modification
GO:0043044 ATP-dependent chromatin remodeling
GO:0051304 chromosome separation
GO:0070932 histone H3 deacetylation
GO:0070933 histone H4 deacetylation
Cellular Component
GO:0000792 heterochromatin
GO:0005634 nucleus
GO:0005694 chromosome
GO:0035861 site of double-strand break
GO:0043596 nuclear replication fork
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000163104
View Gene Order
ENSMUSG00000029920
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca