Version 5.4
Bos taurus Gene: TRIM11
Summary
InnateDB Gene IDBG-641177.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM11
Gene Name E3 ubiquitin-protein ligase TRIM11
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000039246
Encoded Proteins
IDBP-693505
E3 ubiquitin-protein ligase TRIM11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154370:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:2547175-2555050
Strand Forward strand
Band
Transcripts
ENSBTAT00000024852 ENSBTAP00000024852
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0019904 protein domain specific binding
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
GO:0032897 negative regulation of viral transcription
GO:0045087 innate immune response
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046597 negative regulation of viral entry into host cell
GO:0046598 positive regulation of viral entry into host cell
GO:0050768 negative regulation of neurogenesis
GO:0051607 defense response to virus
GO:1902187 negative regulation of viral release from host cell
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000154370
View Gene Order
ENSMUSG00000020455
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_230745
Immune System pathway
REACT_199115
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_229531
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt A0JN74
TrEMBL
UniProt Splice Variant
Entrez Gene 514580
UniGene Bt.34145
RefSeq NM_001077920
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126548
GenPept AAI26549
RNA Seq Atlas 514580
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca