Bos taurus Gene: BT.53629
Summary
InnateDB Gene IDBG-641282.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.53629
Gene Name GEM-interacting protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015144
Encoded Proteins
GEM-interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000089639:
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:3613638-3623376
Strand Forward strand
Band
Transcripts
ENSBTAT00000020147 ENSBTAP00000020147
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005100 Rho GTPase activator activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0007165 signal transduction
GO:0032321 positive regulation of Rho GTPase activity
GO:0034259 negative regulation of Rho GTPase activity
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005622 intracellular
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Rho GTPase cycle pathway
Signaling by Rho GTPases pathway
Signal Transduction pathway
Signaling by Rho GTPases pathway
Rho GTPase cycle pathway
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.53629
RefSeq NM_001083465 XM_005208461 XM_005208462
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas