Version 5.4
Bos taurus Gene: FKBP8
Summary
InnateDB Gene IDBG-641662.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FKBP8
Gene Name peptidyl-prolyl cis-trans isomerase FKBP8
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016264
Encoded Proteins
IDBP-694076
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105701:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:4566171-4574944
Strand Forward strand
Band
Transcripts
ENSBTAT00000021634 ENSBTAP00000021634
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 65 interaction(s) predicted by orthology.
Predicted by orthology
Total 65 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005515 protein binding
GO:0005528 FK506 binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0001708 cell fate specification
GO:0006457 protein folding
GO:0007224 smoothened signaling pathway
GO:0009953 dorsal/ventral pattern formation
GO:0010468 regulation of gene expression
GO:0021904 dorsal/ventral neural tube patterning
GO:0021915 neural tube development
GO:0030510 regulation of BMP signaling pathway
GO:0030513 positive regulation of BMP signaling pathway
GO:0035264 multicellular organism growth
GO:0043010 camera-type eye development
GO:0043066 negative regulation of apoptotic process
GO:0061077 chaperone-mediated protein folding
Cellular Component
GO:0005739 mitochondrion
GO:0005740 mitochondrial envelope
GO:0005789 endoplasmic reticulum membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000105701
View Gene Order
ENSMUSG00000019428
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
INOH website
Insulin receptor signaling pathway
INOH website
Insulin receptor signaling pathway
PID NCI
nfat_3pathway
Role of Calcineurin-dependent NFAT signaling in lymphocytes
Cross-References
SwissProt
TrEMBL F1N2P6 Q05B91
UniProt Splice Variant
Entrez Gene 512356
UniGene Bt.7853
RefSeq NM_001205721
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC122594 DAAA02019044
GenPept AAI22595
RNA Seq Atlas 512356

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca