InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: U2AF2

Summary

InnateDB Gene

IDBG-641756.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

U2AF2

Gene Name

splicing factor U2AF 65 kDa subunit

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002830

Encoded Proteins

IDBP-694154

splicing factor U2AF 65 kDa subunit

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000063244:
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:62327715-62340671

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000003664

ENSBTAP00000003664

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 114 interaction(s) predicted by orthology.

Predicted by orthology
Total	114 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0044822	poly(A) RNA binding
GO:0070742	C2H2 zinc finger domain binding