Version 5.4
Bos taurus Gene: BPIFB1
Summary
InnateDB Gene IDBG-641787.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BPIFB1
Gene Name BPI fold-containing family B member 1 precursor
Synonyms C13H20orf114; C20orf114; LPLUNC1
Species Bos taurus
Ensembl Gene ENSBTAG00000015724
Encoded Proteins
IDBP-694189
long palate, lung and nasal epithelium carcinoma-associated protein 1 precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125999:
The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:63284373-63305522
Strand Forward strand
Band
Transcripts
ENSBTAT00000020875 ENSBTAP00000020875
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008289 lipid binding
Biological Process
GO:0002227 innate immune response in mucosa
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000125999
View Gene Order
ENSMUSG00000027485
View Gene Order
Cross-References
SwissProt
TrEMBL F1MLW2
UniProt Splice Variant
Entrez Gene 282643
UniGene Bt.8897
RefSeq NM_174697 XM_005214500 XM_005214501
HUGO HGNC:16108
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02036430
GenPept
RNA Seq Atlas 282643

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca