Version 5.4
Mus musculus Gene: Bpifb1
Summary
InnateDB Gene IDBG-210291.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bpifb1
Gene Name BPI fold containing family B, member 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000027485
Encoded Proteins
IDBP-210293
BPI fold containing family B, member 1
IDBP-210295
BPI fold containing family B, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125999:
The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:154190818-154220369
Strand Forward strand
Band H1
Transcripts
ENSMUST00000081816 ENSMUSP00000080501
ENSMUST00000028987 ENSMUSP00000028987
ENSMUST00000123017
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008289 lipid binding
Biological Process
GO:0002227 innate immune response in mucosa
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway
GO:0045087 innate immune response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000125999
View Gene Order
ENSBTAG00000015724
Not yet available
Cross-References
SwissProt Q61114
TrEMBL
UniProt Splice Variant
Entrez Gene 228801
UniGene Mm.3783
RefSeq NM_001012392 NM_153418
OMIM
CCDS CCDS16927
HPRD
IMGT
MGI ID MGI:2137431
MGI Symbol Bpifb1
EMBL AL732601 BC060982 BC100436 U46068
GenPept AAA87581 AAH60982 AAI00437 CAM15619
RNA Seq Atlas 228801

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca