Bos taurus Gene: NGEF
Summary
InnateDB Gene IDBG-641819.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NGEF
Gene Name ephexin-1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008942
Encoded Proteins
ephexin-1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000066248:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:113219680-113266318
Strand Reverse strand
Band
Transcripts
ENSBTAT00000011773 ENSBTAP00000011773
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0009987 cellular process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
NRAGE signals death through JNK pathway
G alpha (12/13) signalling events pathway
Rho GTPase cycle pathway
Developmental Biology pathway
Signalling by NGF pathway
Signaling by Rho GTPases pathway
Signaling by GPCR pathway
Axon guidance pathway
p75 NTR receptor-mediated signalling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
EPHA-mediated growth cone collapse pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
EPH-Ephrin signaling pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
EPHA-mediated growth cone collapse pathway
NRAGE signals death through JNK pathway
Signaling by Rho GTPases pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
EPH-Ephrin signaling pathway
G alpha (12/13) signalling events pathway
Axon guidance pathway
Rho GTPase cycle pathway
Signalling by NGF pathway
Developmental Biology pathway
Signal Transduction pathway
p75 NTR receptor-mediated signalling pathway
KEGG
Axon guidance pathway
Axon guidance pathway
INOH
PID NCI
EPHA forward signaling
Regulation of RAC1 activity
Regulation of RhoA activity
Regulation of CDC42 activity
Cross-References
SwissProt
TrEMBL F1MVZ8 Q08DA6
UniProt Splice Variant
Entrez Gene 540756
UniGene Bt.23388
RefSeq NM_001076926
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123858 DAAA02009268
GenPept AAI23859
RNA Seq Atlas 540756