Bos taurus Gene: KCNN1
Summary
InnateDB Gene IDBG-641827.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNN1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008626
Encoded Proteins
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105642:
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:5111700-5134438
Strand Reverse strand
Band
Transcripts
ENSBTAT00000011376 ENSBTAP00000011376
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005516 calmodulin binding
GO:0015269 calcium-activated potassium channel activity
GO:0016286 small conductance calcium-activated potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Ca2+ activated K+ channels pathway
Neuronal System pathway
Potassium Channels pathway
Potassium Channels pathway
Ca2+ activated K+ channels pathway
Neuronal System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BGY2
UniProt Splice Variant
Entrez Gene 408008
UniGene Bt.110426 Bt.29975
RefSeq XM_002688571 XM_005198805 XM_005198806 XM_005198807 XM_005198808 XM_005198809 XM_005208547 XM_005208548 XM_005208549 XM_005208550 XM_005208551 XM_868291
HUGO HGNC:6290
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02019063
GenPept
RNA Seq Atlas 408008